Drug delivery

Scientists at NanoMicrobe have developed a new generation of drug delivery platform. Our technology is suitable for delivering drugs into bacteria, fungi and animal cells.

Biomolecules such as proteins, peptides, polypeptides and analogues, small molecules (drugs), nucleic acids and analogues, synthetic compounds, analogues and derivatives thereof (often referred to as cargo molecules in delivery) have many applications in both prophylactic and therapeutic interventions and also in basic research and drug development process and as diagnostics. However, majority of the prokaryotic and eukaryotic cells are primarily impermeable to above listed molecules/derivatives or analogues, including synthetic compounds used for research and prophylactic/therapeutic applications. Delivery of the above mentioned molecules types into a cell are very important to achieve desired target functions both in-vitro and in-vivo. To achieve a maximum functional effects, the vehicle/cargo complexes has to overcome many extracellular and intracellular hurdles such as extracellular cargo degradation, cell membrane barrier which prevents entry into a cell and unloading or release of cargo molecules inside a cell (often involving endosome escape) for effective function with least cytotoxic effects. Additionally, it is desired to use a delivery vehicle, which is biocompatible, biodegradable, and non hazardous to the public health. There is a dire need for a biocompatible, efficient, nontoxic assisted delivery vehicle.

Nanomicrobe delveloped a biodegradable new generation Nano Drug Delivery  technology for delivery of above listed cargo molecules. Our technology is suitable for both research use and invio applications.